GMEB2 Antikörper (Glucocorticoid Modulatory Element Binding Protein 2) (Cy5)

Details for Product anti-GMEB2 Antibody No. ABIN1704179
Antigen
  • GMEB2
  • P79PIF
  • PIF79
  • AI839884
  • glucocorticoid modulatory element binding protein 2
  • glucocorticoid modulatory element binding protein 2 S homeolog
  • GMEB2
  • gmeb2.S
  • Gmeb2
Reaktivität
Human, Maus, Ratte (Rattus)
36
27
27
2
2
2
2
1
Wirt
Kaninchen
32
4
Klonalität
Polyklonal
Konjugat
Dieser GMEB2 Antikörper ist konjugiert mit Cy5
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
16
12
8
6
5
2
2
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human GMEB2
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere GMEB2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Gmeb2 (GMEB2 Antibody Abstract)
Hintergrund

GMEB-2 is a DNA-binding protein that plays a crucial role modulating transcription upon activation by steroid hormones. GMEB-2 is ubiquitously expressed with preferential expression in developmentally important tissues, such as testis, bone marrow, placenta and fetal tissues. It localizes to the nucleus and cytoplasm and contains a SAND domain near its N-terminus and a C-terminal coiled coil structure. GMEB-2 functions as a homodimer or as a heterodimer with GMEB-1. The formed complex specifically binds to glucocorticoid modulatory elements (GME) in the promoter region of target genes and recruits the histone acetylase CREB binding protein (CBP) during glucocorticoid signaling. This acts to increase sensitivity to low concentrations of glucocorticoids. In addition, GMEB-2 functions as an auxiliary factor required for parvovirus replication.

Synonyms: GMEB2, DNA binding protein p79P, DNA-binding protein p79P, Glucocorticoid modulatory element binding protein 2, Glucocorticoid modulatory element-binding protein 2, GMEB 2, GMEB-2, Gmeb2, GMEB2_HUMAN, KIAA1269, P79P, Parvovirus initiation factor p79, P p79, P79, RP4 663D7.1.

Gen-ID 26205
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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