GEMIN7 Antikörper (Gem (Nuclear Organelle) Associated Protein 7) (Cy5)

Details for Product anti-GEMIN7 Antibody No. ABIN1704176
Antigen
  • SIP3
  • GEMIN7
  • Gemin7
  • 2400008I04Rik
  • AI120175
  • AI461688
  • gem nuclear organelle associated protein 7
  • gem (nuclear organelle) associated protein 7
  • GEMIN7
  • Gemin7
Reaktivität
Human, Maus, Ratte (Rattus)
47
25
17
1
1
1
1
Wirt
Kaninchen
39
8
Klonalität
Polyklonal
Konjugat
Dieser GEMIN7 Antikörper ist konjugiert mit Cy5
4
3
3
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
27
17
12
3
2
2
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human Gemin 7
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere GEMIN7 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Gemin 7 (GEMIN7 Antibody Abstract)
Hintergrund

Gemin7 is a 131 amino acid protein encoded by the mouse gene Gemin7. Gemin7, along with Gemin6, is a significant component of the the large multiprotein human SMN complex. The SMN complex functions as an assembly machine for small nuclear ribonucleoproteins (snRNPs)-the major components of the spliceosome. The survival of motor neurons (SMN) protein, a product of the disease gene of the common neurodegenerative disease, spinal muscular atrophy, is also part of the SMN complex. Although Gemin6 and Gemin7 have no significant sequence similarity with Sm proteins, both adopt canonical Sm folds. Moreover, Gemin6 and Gemin7 exist as a heterodimer, and interact with each other via an interface similar to that which mediates interactions among the Sm proteins. The Gemin6/Gemin7 complex binds to Sm proteins and might help organize Sm proteins for formation of Sm rings on snRNA targets.

Synonyms: SIP3, Gemin7, Gemin-7, GEMI7_HUMAN.

Gen-ID 79760
Pathways Ribonucleoprotein Complex Subunit Organization
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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