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GEMIN7 Antikörper (AA 21-120) (Cy5)

Der Kaninchen Polyklonal Anti-GEMIN7-Antikörper wurde für FACS, IF (cc) und IF (p) validiert. Er ist geeignet, GEMIN7 in Proben von Human und Ratte zu detektieren.
Produktnummer ABIN1704176

Kurzübersicht für GEMIN7 Antikörper (AA 21-120) (Cy5) (ABIN1704176)

Target

Alle GEMIN7 Antikörper anzeigen
GEMIN7 (Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7))

Reaktivität

  • 39
  • 16
  • 10
  • 1
  • 1
  • 1
  • 1
Human, Ratte

Wirt

  • 35
  • 4
Kaninchen

Klonalität

  • 36
  • 3
Polyklonal

Konjugat

  • 12
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GEMIN7 Antikörper ist konjugiert mit Cy5

Applikation

  • 15
  • 13
  • 13
  • 12
  • 12
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 15
    • 10
    • 1
    • 1
    • 1
    • 1
    AA 21-120

    Kreuzreaktivität

    Human, Ratte

    Homologie

    Mouse,Dog,Cow,Horse,Chicken

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Gemin 7

    Isotyp

    IgG
  • Applikationshinweise

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    GEMIN7 (Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7))

    Andere Bezeichnung

    Gemin 7

    Hintergrund

    Synonyms: SIP3, Gemin7, Gemin-7, GEMI7_HUMAN.

    Background: Gemin7 is a 131 amino acid protein encoded by the mouse gene Gemin7. Gemin7, along with Gemin6, is a significant component of the the large multiprotein human SMN complex. The SMN complex functions as an assembly machine for small nuclear ribonucleoproteins (snRNPs)-the major components of the spliceosome. The survival of motor neurons (SMN) protein, a product of the disease gene of the common neurodegenerative disease, spinal muscular atrophy, is also part of the SMN complex. Although Gemin6 and Gemin7 have no significant sequence similarity with Sm proteins, both adopt canonical Sm folds. Moreover, Gemin6 and Gemin7 exist as a heterodimer, and interact with each other via an interface similar to that which mediates interactions among the Sm proteins. The Gemin6/Gemin7 complex binds to Sm proteins and might help organize Sm proteins for formation of Sm rings on snRNA targets.

    Gen-ID

    79760

    Pathways

    Ribonucleoprotein Complex Subunit Organization
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