CUTC Antikörper (AA 201-273) (Cy5)

Produktnummer ABIN1703878

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CUTC in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CUTC Antikörper (AA 201-273) (Cy5) (ABIN1703878)

Target: CUTC (CutC Copper Transporter Homolog (CUTC))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CUTC Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CUTC Antikörper (Cy5)

Bindungsspezifität: AA 201-273

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CUTC

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CUTC

Target: CUTC (CutC Copper Transporter Homolog (CUTC))

Andere Bezeichnung: CUTC

Hintergrund:

Synonyms: CGI 32, CGI32, Copper homeostasis protein cutC homolog, cutC, CutC copper transporter homolog E. coli, CUTC_HUMAN, RP11-483F11.3.

Background: Copper is an essential micronutrient used as a co-factor for several essential enzymes in all living organisms. Due to the high toxicity of copper, its metabolism is tightly regulated and defects in this regulation can cause Menkes (deficiency) or Wilson (accumulation) disease in various tissue. CUTC (cutC copper transporter homolog (E. coli)), also known as CGI-32, is a 273 amino acid protein belonging to the cutC family. CUTC is involved in copper homeostasis and is encoded by a gene located on human chromosome 10, which contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency and trisomy 10.

Gen-ID: 51076

Pathways: Transition Metal Ion Homeostasis