TRIM22 Antikörper (AA 231-330) (Cy5)

Produktnummer ABIN1703706

Dieses Anti-TRIM22-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TRIM22 in WB, IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für TRIM22 Antikörper (AA 231-330) (Cy5) (ABIN1703706)

Target: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM22 Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-TRIM22 Antikörper (Cy5)

Bindungsspezifität: AA 231-330

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Trim22

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TRIM22

Target: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Andere Bezeichnung: Trim22/Staf-50

Hintergrund:

Synonyms: 50 kDa stimulated trans acting factor, RING finger protein 94, RNF94, Staf 50, STAF50, Stimulated trans acting factor 50 kDa, Stimulated Trans Acting Factor homolog of Mouse Rpt 1 gene, Trim22, Tripartite binding mot 22, Tripartite mot containing protein 22, TTRIM22RIM22, TRI22_HUMAN.

Background: The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. Staf-50 (50 kDa-stimulated trans-acting factor), also known as TRIM22 (tripartite motif-containing 22), RNF94 or GPSTAF50, is a 498 amino acid cytoplasmic protein that belongs to the TRIM family and, characteristic of TRIM family members, contains one RING-type zinc finger, one B box-type zinc finger and one SPRY domain. Induced by IFN-å, and IFN-, Staf-50 is strongly expressed in ovary, spleen, thymus and peripheral blood leukocytes where it is thought to mediate the antiviral effects of IFN proteins. Additionally, Staf-50 is present in leukemic cells, suggesting a role in cancer formation and metastasis. Staf-50 exists as two alternatively spliced isoforms which are encoded by a gene that maps to human chromosome 11.

Gen-ID: 10346