Factor Viiia Light Chain (Light Chain) Antikörper (Cy5)

Produktnummer ABIN1703614

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Factor Viiia Light Chain in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Factor Viiia Light Chain (Light Chain) Antikörper (Cy5) (ABIN1703614)

Target: Factor Viiia Light Chain

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Cy5

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: Light Chain

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Factor VIIIa light chain

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Factor Viiia Light Chain

Hintergrund:

Synonyms: coagulation factor VIII, Ahf, Antihemophilic factor, Coagulation factor VIII, Coagulation factor VIII associated protein b, Coagulation factor VIII isoform b, Coagulation factor VIII procoagulent component, Coagulation factor VIIIc, Dna segment on chromosome x unique 1253 expressed sequence, Dxs1253e, F8, F8 protein, F8b, F8c, FactorVIII, FVIII, Hema, Hema coagulation factor VIIIc procoagulent component, Hemophilia a, Hemophilia classic, OTTHUMP00000061446, Procoagulant component, AHF, DXS1253E, F8B, F8C, FVIII, HEMA, FA8_HUMAN.

Background: This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008].