MIXL1 Antikörper (AA 101-200) (Cy3)

Produktnummer ABIN1703355

Dieses Anti-MIXL1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MIXL1 in WB, IF (cc) und IF (p). Geeignet für Maus.

Kurzübersicht für MIXL1 Antikörper (AA 101-200) (Cy3) (ABIN1703355)

Target: MIXL1 (Mix Paired-Like Homeobox (MIXL1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MIXL1 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-MIXL1 Antikörper (Cy3)

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Maus

Homologie: Human,Rat,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MIXL1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MIXL1

Target: MIXL1 (Mix Paired-Like Homeobox (MIXL1))

Andere Bezeichnung: MIXL1

Hintergrund:

Synonyms: hMix, Homeobox protein MIXL1, Homeodomain protein 1, Homeodomain protein MIX, MILD1, MIX, Mix.1, Mix.1 homeobox-like protein, Mix1 homeobox-like 1, MIX1 homeobox-like protein 1, Mixl1, MIXL1_HUMAN.

Background: The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and in the control of gene expression. MIXL1 (Mix1 homeobox-like 1), also known as MIXL, is a 232 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Expressed in lymph tissues, MIXL1 functions as a transcription factor that plays an essential role in axial mesendoderm morphogenesis and endoderm formation and is also required for cellular differentiation during blood development. Additionally, MIXL1 is involved in maturation of heart and gut tissue during embryogenesis and may also act as a negative regulator of brachyury expression. Overexpression of MIXL1 is associated with non-Hodgkin and Hodgkin lymphomas, suggesting a role in carcinogenesis.

Gen-ID: 83881