FOSB Antikörper (pSer27) (Cy3)

Produktnummer ABIN1702894

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FOSB in WB und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für FOSB Antikörper (pSer27) (Cy3) (ABIN1702894)

Target: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOSB Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-FOSB Antikörper (Cy3)

Bindungsspezifität: pSer27

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Fos B around the phosphorylation site of Ser27

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FOSB

Target: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Andere Bezeichnung: FosB

Hintergrund:

Synonyms: Fos B phospho S27, p-Fos B phospho S27, p-FosB phospho S27, FBJ murine osteosarcoma viral oncogene homolog B, FOS B, FOS-B, FBJ osteosarcoma oncogene B, FosB, G0/G1 switch regulatory protein 3, G0S3, GOS3, GOSB, MGC42291, Oncogene FOS B, Protein fosB, fosB, G0/G1 switch regulatory protein 3, G0S3, GOS 3, GOS B, GOSB, Oncogene FOS B, Oncogene FOSB, Protein fos B, DKFZp686C0818, FOSB_HUMAN.

Background: The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70 % homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.

Gen-ID: 2354