STRA6 Antikörper (AA 151-250) (Cy3)

Produktnummer ABIN1702790

Der Kaninchen Polyklonal Anti-STRA6-Antikörper wurde für IF (cc) und IF (p) validiert. Er ist geeignet, STRA6 in Proben von Human zu detektieren.

Kurzübersicht für STRA6 Antikörper (AA 151-250) (Cy3) (ABIN1702790)

Target: STRA6 (Stimulated By Retinoic Acid 6 (STRA6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STRA6 Antikörper ist konjugiert mit Cy3

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-STRA6 Antikörper (Cy3)

Bindungsspezifität: AA 151-250

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human STRA6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu STRA6

Target: STRA6 (Stimulated By Retinoic Acid 6 (STRA6))

Andere Bezeichnung: STRA6

Hintergrund:

Synonyms: Stimulated by retinoic acid gene 6 protein homolog, STRA6_HUMAN.

Background: STRA6 is a 667 amino acid, multi-pass cell membrane protein. Stra6 functions as a cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Ultimately increasing cellular retinol uptake from the retinol-RBP complex, Stra6 removes retinol from RBP/RPB4 and transports it across the plasma membrane, where it is metabolized. Stra6 is broadly expressed, with 4 named isoforms that exist as a result of alternative splicing events. Mutations in the gene encoding Stra6 cause Matthew-Wood Syndrome, also known as Spear Syndrome. This syndrome is characterized by anophtalmia, mild facial dysmorphism and malformations of the heart, lung and diaphragm. The Stra6 gene maps to chromosome 15q24.1.

Gen-ID: 64220

UniProt: Q9BX79

Pathways: Feeding Behaviour