ZBTB48 Antikörper (AA 451-550) (Cy3)

Produktnummer ABIN1702553

Der Kaninchen Polyklonal Anti-ZBTB48-Antikörper wurde für IF (cc) und IF (p) validiert. Er ist geeignet, ZBTB48 in Proben von Human zu detektieren.

Kurzübersicht für ZBTB48 Antikörper (AA 451-550) (Cy3) (ABIN1702553)

Target: ZBTB48 (Zinc Finger and BTB Domain Containing 48 (ZBTB48))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZBTB48 Antikörper ist konjugiert mit Cy3

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ZBTB48 Antikörper (Cy3)

Bindungsspezifität: AA 451-550

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZBTB48/ZNF855

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ZBTB48

Target: ZBTB48 (Zinc Finger and BTB Domain Containing 48 (ZBTB48))

Andere Bezeichnung: ZBTB48/ZNF855

Hintergrund:

Synonyms: 0610011D15Rik, AI327031, GLI Kruppel family member HKR3, HKR3, Krueppel related zinc finger protein 3, Krueppel-related zinc finger protein 3, OTTMUSP00000031803, pp9964, Protein HKR3, RP23-445E20.3, ZBT48_HUMAN, ZBTB 48, Zbtb48, Zinc finger and BTB domain containing 48, Zinc finger and BTB domain containing protein 48, Zinc finger and BTB domain-containing protein 48, Zinc finger protein 855, ZNF855.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 48 (ZBTB48), also known as Kruppel-related zinc finger protein 3 or HKR3, is a 688 amino acid member of the Kr_ppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB48 is expressed in the adrenal gland and neuroblastoma cell lines. ZBTB48 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB48 functions as a transcription regulator.

Gen-ID: 3104