SPAG9 Antikörper (AA 101-188) (Cy3)

Produktnummer ABIN1702341

Dieses Anti-SPAG9-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SPAG9 in IF (cc) und IF (p). Geeignet für Maus.

Kurzübersicht für SPAG9 Antikörper (AA 101-188) (Cy3) (ABIN1702341)

Target: SPAG9 (Sperm Associated Antigen 9 (SPAG9))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPAG9 Antikörper ist konjugiert mit Cy3

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-SPAG9 Antikörper (Cy3)

Bindungsspezifität: AA 101-188

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Sheep,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human JLP/JIP-4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SPAG9

Target: SPAG9 (Sperm Associated Antigen 9 (SPAG9))

Andere Bezeichnung: JLP/JIP-4

Hintergrund:

Synonyms: C jun amino terminal kinase interacting protein 4, c Jun NH2 terminal kinase associated leucine zipper protein, FLJ13450, FLJ14006, FLJ34602, HLC 4, HLC 4 protein, HLC 6, HLC4, HLC4 protein, HLC6, HSS, Human lung cancer protein 6, Human lung cancer protein 6, JIP 4, JIP 4, JIP4, JNK associated leucine zipper protein 1, JNK associated leucine zipper protein, JNK interacting protein 4, JNK interacting protein 4, JNK interacting protein, JNK/SAPK associated protein, KIAA0516, Lung cancer oncogene 4, MAPK8IP4, Max binding protein, MGC117291, MGC14967, MGC74461, Mitogen activated protein kinase 8 interacting protein 4, Mitogen activated protein kinase 8 interacting protein 4, PHET, PIG 6, PIG6, proliferation inducing gene 6, Protein highly expressed in testis, SPAG 9, SPAG9, Sperm associated antigen 9, Sperm specic protein, Sperm surface protein, Sunday driver drosophila homolog, Sunday driver 1, SYD1, JIP4_HUMAN.

Background: JIP-4 is a 1,321 amino acid protein encoded by the human gene SPAG9. It contains a large N-terminal extracellular domain, a short transmembrane helical domain, and a cytoplasmic domain. There are 6 N-glycosylation sites, several phosphorylation sites for cAMP/cGMP-dependent protein kinase, protein kinase C, and casein kinase II, and 10 putative myristoylation sites. There is also a leucine zipper motif, with 6 leucine repeats, that may aid in dimerization since there is no upstream basic domain characteristic of DNA binding proteins. The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP-4 is a cytoplasmic, perinuclear protein that has eight known isoforms whose expression varies by tissue and disease state.

Gen-ID: 9043

UniProt: O60271

Pathways: Regulation of Muscle Cell Differentiation