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m1ip1 Antikörper (AA 21-120) (Cy3)

Der Kaninchen Polyklonal Anti-m1ip1-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, m1ip1 in Proben von Human und Maus zu detektieren.
Produktnummer ABIN1702211

Kurzübersicht für m1ip1 Antikörper (AA 21-120) (Cy3) (ABIN1702211)

Target

Alle m1ip1 Antikörper anzeigen
m1ip1 (Mid1-Interacting Protein 1 (m1ip1))

Reaktivität

  • 36
  • 17
  • 3
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 32
  • 3
  • 1
Kaninchen

Klonalität

  • 35
  • 1
Polyklonal

Konjugat

  • 19
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser m1ip1 Antikörper ist konjugiert mit Cy3

Applikation

  • 31
  • 12
  • 12
  • 12
  • 8
  • 6
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 21-120

    Kreuzreaktivität

    Human, Maus

    Homologie

    Rat,Cow,Sheep,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human SLAP

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    m1ip1 (Mid1-Interacting Protein 1 (m1ip1))

    Andere Bezeichnung

    SLAP

    Hintergrund

    Synonyms: hSLAP, SLA 1, SLA, SLA1, SLAP 1, SLAP, SLAP-1, SLAP1, SLAP1_HUMAN, Src like adapter, Src like adapter protein 1, Src like adaptor, SRC-like-adapter, Src-like-adapter protein 1.

    Background: The Src homology 3 (SH3) region is a small protein domain of approximately 60 amino acids present in a large group of proteins. In general, it exists in association with catalytic domains, as in the nonreceptor protein-tyrosine kinases and phospholipase C-? within structural proteins, such as spectrin or Myosin, and in small adapter proteins, such as Crk and GRB2. SH3 domains are often accompanied by SH2 domains of 100 amino acids, which bind to tyrosine-phosphorylated regions of target proteins, frequently linking activated growth factors to putative signal transduction proteins. The functions of SH3 domains are not as well defined. Deletion or mutation of SH3 domains generally activate the transforming potential of nonreceptor tyrosine kinases, suggesting that SH3 mediates negative regulation of an intrinsic transforming activity. 3BP1 has been identified as a protein with a high affinity proline-rich binding site for the SH3 domain of c-Abl p120. A similar putative adapter protein, designated Slap, for Src-like adapter protein, has been cloned. Slap contains a single SH2 and SH3 domain that exhibits homology with those from members of the Src kinase family. The N- and C-termini, however, are unique.

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