ERMAP Antikörper (AA 61-120) (Cy3)

Produktnummer ABIN1702090

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ERMAP in IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ERMAP Antikörper (AA 61-120) (Cy3) (ABIN1702090)

Target: ERMAP (erythroblast Membrane-Associated Protein (Scianna Blood Group) (ERMAP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERMAP Antikörper ist konjugiert mit Cy3

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ERMAP Antikörper (Cy3)

Bindungsspezifität: AA 61-120

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ERMAP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ERMAP

Target: ERMAP (erythroblast Membrane-Associated Protein (Scianna Blood Group) (ERMAP))

Andere Bezeichnung: ERMAP

Hintergrund:

Synonyms: ERMAP, ERMAP_HUMAN, Erythroblast membrane associated protein, Erythroid membrane associated protein, Erythroid membrane-associated protein, hERMAP, MGC118810, MGC118811, MGC118812, MGC118813, PRO2801, Radin blood group Rd, Radin blood group antigen, RD, SC, Scianna blood group Sc, Scianna blood group antigen.

Background: ERMAP is a single-pass type one membrane protein that belongs to the immunoglobulin superfamily. Expressed in cord blood, fetal liver and adult bone marrow, ERMAP is thought to function as a cell adhesion molecule in erythroid cells and is responsible for expression of the Scianna/Radin (Sc/Rd) blood group antigen system. The Sc/Rd system is comprised of seven antigens that are present on the surface of red blood cells and have a variety of functions ranging from protein transport to cell adhesion. These seven blood antigens can differ in their expression within a population and may sometimes differ between mother and child. A fetus expressing different blood antigens than its mother may cause the mother to produce against the fetal blood. This condition is known as hemolytic disease of the newborn (HDN) and is characterized by jaundice, anemia and in some cases, infant death.

Gen-ID: 114625