TSPAN32 Antikörper (AA 101-200) (Cy3)

Produktnummer ABIN1701877

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TSPAN32 in IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für TSPAN32 Antikörper (AA 101-200) (Cy3) (ABIN1701877)

Target: TSPAN32 (Tetraspanin 32 (TSPAN32))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSPAN32 Antikörper ist konjugiert mit Cy3

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-TSPAN32 Antikörper (Cy3)

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TSPAN32

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TSPAN32

Target: TSPAN32 (Tetraspanin 32 (TSPAN32))

Andere Bezeichnung: PHEMX/ART1

Hintergrund:

Synonyms: ART 1, FLJ17158, FLJ97586, MGC22455, PHEMX/ART1, Pan hematopoietic expression, PHEMX, PHMX, tetraspanin 32, Tetraspanin, tetraspanin32, TSPAN32, TSSC6, Tumor suppressing STF cDNA 6, Tumor suppressing subchromosomal transferable fragment cDNA 6, Tumor suppressing subtransferable candidate 6.

Background: Phemx is a member of the tetraspanin (TM4SF) family of proteins that may be involved in transmembrane signal transduction, regulation of cell proliferation, differentiation and motility. Phemx is a multi-pass membrane protein containing intracellular N- and C-terminal domains, four transmembrane domains and two extracellular loops. It is ubiquitously expressed from early embryogenesis through adulthood. Phemx exhibits predominant expression in hematopoietic tissues suggesting a role in hematopoietic-cell function. In association with the Integrin IIb/Integrin _3 complex, Phemx functions to stabilize arterial thrombi in platelets and regulate outside-in? signaling. This interaction may be important in the process of wound healing. The gene encoding Phemx is located in an important tumor-suppressor gene region that has been associated with Beckwith-Wiedemann syndrome as well as a variety of cancers.

Gen-ID: 10077