C4BP Antikörper (AA 1-100) (Biotin)

Produktnummer ABIN1701590

Der Kaninchen Polyklonal Anti-C4BP-Antikörper wurde für WB, ELISA, IHC (fro) und IHC (p) validiert. Er ist geeignet, C4BP in Proben von Human zu detektieren.

Kurzübersicht für C4BP Antikörper (AA 1-100) (Biotin) (ABIN1701590)

Target: C4BP (C4-Binding Protein (C4BP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C4BP Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-C4BP Antikörper (Biotin)

Bindungsspezifität: AA 1-100

Kreuzreaktivität: Human

Homologie: Rat,Dog

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C4 binding protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu C4BP

Target: C4BP (C4-Binding Protein (C4BP))

Andere Bezeichnung: C4 binding protein

Hintergrund:

Synonyms: C4b binding protein beta chain, C4b-binding protein beta chain, C4BP, C4BPB, C4BPB_HUMAN, Complement component 4 binding protein beta, Complement component 4 binding protein beta chain, Complement component 4-binding protein beta, OTTHUMP00000034288, OTTHUMP00000034289, OTTHUMP00000034375, OTTHUMP0000003474, Proline rich protein, PRP.

Background: C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants