OVOL2 Antikörper (AA 75-180) (Biotin)

Produktnummer ABIN1701545

Der Kaninchen Polyklonal Anti-OVOL2-Antikörper wurde für WB, ELISA, IHC (fro) und IHC (p) validiert. Er ist geeignet, OVOL2 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für OVOL2 Antikörper (AA 75-180) (Biotin) (ABIN1701545)

Target: OVOL2 (Ovo-Like 2 (OVOL2))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OVOL2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-OVOL2 Antikörper (Biotin)

Bindungsspezifität: AA 75-180

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OVOL2/ZNF339

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu OVOL2

Target: OVOL2 (Ovo-Like 2 (OVOL2))

Andere Bezeichnung: OVOL2/ZNF339

Hintergrund:

Synonyms: bA504H3.3, EUROIMAGE566589, hOvo 2, hOvo2, Ovo like 2 Drosophila, Ovo like 2, OVOL 2, Transcription factor Ovo like 2, Zinc finger protein 339, ZNF 339, ZNF339, OVOL2_HUMAN.

Background: The Ovo family of zinc-finger transcription factors encode evolutionarily conserved genes including those from Caenorhabditis elegans, Drosophila melanogaster, mouse and human. Members of the Ovo family include Ovol1 and Ovol2. Ovol1 acts as a transcriptional repressor by interacting with key developmental signaling pathways such as Wnt and TGF-/BMP. Specifically, Ovol1 represses c-Myc and Id2 genes and establishes a balance between proliferation and differentiation of progenitor cells. Deletion of Ovol1 in mice leads to germ cell degeneration and defective sperm production in adult males. Ovol1 has also been shown to repress itself as well as Ovol2, which is thought to regulate neural development and vascular angiogenesis during embryogenesis.

Gen-ID: 58495

Pathways: Tube Formation