GDI1 Antikörper (AA 1-100) (Biotin)

Produktnummer ABIN1701516

Dieses Anti-GDI1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GDI1 in ELISA, IHC (p) und IHC (fro). Geeignet für Maus und Schimpanse.

Kurzübersicht für GDI1 Antikörper (AA 1-100) (Biotin) (ABIN1701516)

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Reaktivität: Maus, Schimpanse

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDI1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-GDI1 Antikörper (Biotin)

Bindungsspezifität: AA 1-100

Kreuzreaktivität: Schimpanse, Maus

Homologie: Human,Rat,Cow,Sheep,Pig,Rabbit,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GDI1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu GDI1

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Andere Bezeichnung: GDI1

Hintergrund:

Synonyms: 1A, FLJ41411, GDI-1, gdi1, GDIA_HUMAN, GDIL, GDP dissociation inhibitor 1, Guanosine diphosphate dissociation inhibitor 1, Mental retardation X-linked 41, Mental retardation X-linked 48, MRX41, MRX48, Oligophrenin 2, Oligophrenin-2, OPHN2, Protein XAP 4, Protein XAP-4, Protein XAP4, Rab GDI alpha, Rab GDP dissociation inhibitor alpha, RABGD1A, RABGDIA, XAP 4.

Background: Rab proteins, a family of Ras-related small GTP-binding proteins, play a key role in regulating intracellular vesicle trafficking (1?). Rab GDP dissociation inhibitor (Rab GDI or GDI2) forms a soluble complex with Rab proteins and thereby prevents the exchange of GDP for GTP (1?). In mammals, there exist two major isoforms, Rab GDI alpha (also known as XAP-4) and Rab GDI beta (1,4). While the mammalian Rab GDI beta-genes are ubiquitously expressed, the Rab GDI ?genes are predominantly brain-specific (1). Since it is expressed predominantly in neural and sensory tissues, Rab GDI a may serve a specific function in neural signal transmission (5). The gene sequences for the Rab GDI proteins are extremely conserved in evolution, with substantial homology preserved across three eukaryotic kingdoms (5).

Gen-ID: 2664