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Glutaredoxin 2 Antikörper (AA 101-164) (Biotin)

This anti-Glutaredoxin 2 antibody (ABIN1701049) is a Rabbit Polyclonal antibody detecting Glutaredoxin 2 in WB, ELISA, IHC (p), IHC (fro). Suitable for Human, Rat.
Produktnummer ABIN1701049

Quick Overview for Glutaredoxin 2 Antikörper (AA 101-164) (Biotin) (ABIN1701049)

Target

Alle Glutaredoxin 2 (GRX2) Antikörper anzeigen
Glutaredoxin 2 (GRX2)

Reaktivität

  • 48
  • 22
  • 9
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Ratte

Wirt

  • 42
  • 6
Kaninchen

Klonalität

  • 46
  • 2
Polyklonal

Konjugat

  • 23
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Glutaredoxin 2 Antikörper ist konjugiert mit Biotin

Applikation

  • 34
  • 22
  • 13
  • 13
  • 11
  • 10
  • 7
  • 7
  • 6
  • 3
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 15
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 101-164

    Kreuzreaktivität

    Human, Ratte

    Homologie

    Mouse,Dog,Cow,Sheep,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Glutaredoxin 2

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    Glutaredoxin 2 (GRX2)

    Andere Bezeichnung

    Glutaredoxin 2

    Hintergrund

    Synonyms: GRX2, CGI-133, Glutaredoxin-2, mitochondrial, GLRX2

    Background: Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.

    Gen-ID

    51022

    UniProt

    Q9NS18

    Pathways

    Cell RedoxHomeostasis
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