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CAPG Antikörper (AA 251-348) (Biotin)

Der Rabbit Polyclonal Anti-CAPG-Antikörper wurde für ELISA, IHC (p), IHC (fro) validiert. Er ist geeignet, CAPG in Proben von Human zu detektieren.
Produktnummer ABIN1700984

Kurzübersicht für CAPG Antikörper (AA 251-348) (Biotin) (ABIN1700984)

Target

Alle CAPG Antikörper anzeigen
CAPG (Capping Protein (Actin Filament), Gelsolin-Like (CAPG))

Reaktivität

  • 56
  • 15
  • 9
  • 1
Human

Wirt

  • 51
  • 2
  • 2
  • 1
Kaninchen

Klonalität

  • 51
  • 4
Polyklonal

Konjugat

  • 25
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CAPG Antikörper ist konjugiert mit Biotin

Applikation

  • 29
  • 18
  • 13
  • 13
  • 11
  • 8
  • 7
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 12
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-348

    Homologie

    Human,Mouse,Rat,Dog,Cow,Sheep,Horse

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Actin Regulatory Protein CAPG

    Isotyp

    IgG
  • Applikationshinweise

    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    CAPG (Capping Protein (Actin Filament), Gelsolin-Like (CAPG))

    Andere Bezeichnung

    Actin Regulatory Protein CAPG

    Hintergrund

    Synonyms: Actin capping protein GCAP39, Actin regulatory protein CAP G, Actin regulatory protein CAP-G, AFCP, CAPG, CAPG_HUMAN, Capping protein actin filament gelsolin like, Capping protein gelsolin like, gCap39, Gelsolin like capping protein, Macrophage capping protein, Macrophage-capping protein, mbh1, MCP, Myc basic mot homolog 1.

    Background: Caldesmon, Filamin 1, Nebulin, Plastin, ADF, Gelsolin, CapG, Dematin and Cofilin are differentially expressed Actin-binding proteins. Both muscular (CDh) and non-muscular (CD1) forms of Caldesmon bind to Actin as well as to Calmodulin and Myosin. CDh is expressed predominantly on thin filaments in smooth muscle, whereas CD1 is widely expressed in non-muscle tissues and cells. CapG, also designated Actin-regulatory protein and macrophage-capping protein, is a macrophage-specific protein that reversibly blocks the barbed ends of Actin filaments, but does not sever preformed ones. The interactions of CapG with Actin may be important in the regulation of nuclear and cytoplasmic structures. CapG is a calcium-sensitive DNA-binding protein that plays a role in macrophage function. It is expressed in macrophages and macrophage-like cells and can localize both to the nucleus and the cytoplasm.

    Gen-ID

    822

    Pathways

    Regulation of Actin Filament Polymerization
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