HCCS Antikörper (AA 51-150) (Biotin)

Produktnummer ABIN1700964

Dieser Anti-HCCS Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von HCCS in ELISA, IHC (p) und IHC (fro). Geeignet für Maus und Ratte.

Kurzübersicht für HCCS Antikörper (AA 51-150) (Biotin) (ABIN1700964)

Target: HCCS (Holocytochrome C Synthase (HCCS))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HCCS Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-HCCS Antikörper (Biotin)

Bindungsspezifität: AA 51-150

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HCCS

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu HCCS

Target: HCCS (Holocytochrome C Synthase (HCCS))

Andere Bezeichnung: HCCS

Hintergrund:

Synonyms: CCHL, DKFZp779I1858, EC 4.4.1.17, Holocytochrome c synthase cytochrome c heme lyase, Holocytochrome c type synthase, MCOPS7, OTTHUMP00000022903, OTTHUMP00000022904, OTTHUMP00000022905, OTTMUSP00000021173, OTTMUSP00000021174, RGD1563855, RP23-37L2.1, CCHL_HUMAN.

Background: HCCS is a 79 amino acid protein that may act as a tumor suppressor, promoting the apoptosis of cancer cells. Expressed in leukocytes, lung, spleen, liver, heart, kidney, muscle and uterine cervix, HCCS-1 is down-regulated in cervical cancers. The gene encoding HCCS-1 maps to human chromosome 15q25.1. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and comprises about 3 % of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.

Gen-ID: 3052

UniProt: P53701