DMWD Antikörper (AA 501-600) (Biotin)

Produktnummer ABIN1700853

Dieses Anti-DMWD-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DMWD in WB, ELISA, IHC (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für DMWD Antikörper (AA 501-600) (Biotin) (ABIN1700853)

Target: DMWD (Dystrophia Myotonica, WD Repeat Containing (DMWD))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DMWD Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-DMWD Antikörper (Biotin)

Bindungsspezifität: AA 501-600

Homologie: Human,Mouse,Rat,Cow

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DMWD/DMRN9

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu DMWD

Target: DMWD (Dystrophia Myotonica, WD Repeat Containing (DMWD))

Andere Bezeichnung: DMWD/DMRN9

Hintergrund:

Synonyms: dystrophia myotonica containing WD repeat mot,D19S593E, DM 9, DM9, DMR N9, DMR N9 protein, DMRN 9, DMRN9, DMWD, DMWD_HUMAN, Dystrophia myotonica containing WD repeat mot, Dystrophia myotonica containing WD repeat mot protein, Dystrophia myotonica WD repeat containing protein, Dystrophia myotonica WD repeat-containing protein, Dystrophia myotonica-containing WD repeat mot protein, Gene59, Protein 59, Protein DMR-N9.

Background: DMWD is a 674 amino acid protein containing five WD repeats. DMWD may play a role in the development of mental symptoms in severe cases of myotonic dystrophy, a chronic multisystemic disease characterized by wasting of the muscles, heart conduction defects, cataracts, endocrine changes and myotonia. The DMWD gene is located upstream of the DMPK gene and is prominently expressed in tissues affected in myotonic dystrophy patients. DMWD may also contribute to regulation in meiosis. DMWD is expressed in kidney and spleen, with strongest expression in brain, liver and testis. The gene encoding DMWD maps to human chromosome 19q13.32 and mouse chromosome 7 A3.

Gen-ID: 1762