CAPRIN2 Antikörper (AA 101-200) (Biotin)

Produktnummer ABIN1700777

Der Kaninchen Polyklonal Anti-CAPRIN2-Antikörper wurde für WB, ELISA, IHC (fro) und IHC (p) validiert. Er ist geeignet, CAPRIN2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für CAPRIN2 Antikörper (AA 101-200) (Biotin) (ABIN1700777)

Target: CAPRIN2 (Caprin Family Member 2 (CAPRIN2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAPRIN2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CAPRIN2 Antikörper (Biotin)

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CAPRIN2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu CAPRIN2

Target: CAPRIN2 (Caprin Family Member 2 (CAPRIN2))

Andere Bezeichnung: CAPRIN2

Hintergrund:

Synonyms: C1q domain-containing protein 1, C1QDC1, CAPR2_HUMAN, Caprin family member 2, Caprin-2, caprin2, Cytoplasmic activation/proliferation-associated protein 2, EEG 1, EEG1, Gastric cancer multidrug resistance-associated protein, KIAA1873, Protein EEG-1, RNA granule protein 140, RNG140.

Background: Caprin2 is 1127 amino acid highly conserved protein that is ubiquitously expressed with highest levels of expression in brain and spleen. Caprin2 stabilizes cytosolic _-catenin and enhances LEF-1 dependent reporter gene activity as well as the expression of Wnt target genes in mammalian cells. Caprin2 promotes LRP5/6 phosphorylation by GSK-3 and enhances the interaction between Axin and LRP5/6. It is suggested that Caprin2 functions as a proapoptotic inhibitor of the cell cycle. Nine isoforms of Caprin2 exist due to alternative splicing events.

Gen-ID: 65981

UniProt: Q6IMN6