Iglk (AA 101-200) Antikörper (Biotin)

Produktnummer ABIN1700701

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch in WB, ELISA und IHC (fro). Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Iglk (AA 101-200) Antikörper (Biotin) (ABIN1700701)

Target: Iglk

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IGLK

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Antigendetails

Target: Iglk

Hintergrund:

Synonyms: ATP:D-hexose 6 phosphotransferase, FGQTL3, GCK, GK, GLK, Glucokinase, Hexokinase D, Hexokinase D, pancreatic isozyme, Hexokinase type IV, Hexokinase-4, Hexokinase-D, HHF3, HK IV, HK4, HXK4_HUMAN, HXKP, LGLK, MODY2.

Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq, Apr 2009].