DGAT2 Antikörper (AA 251-360) (Biotin)

Produktnummer ABIN1700641

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DGAT2 in WB, ELISA, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DGAT2 Antikörper (AA 251-360) (Biotin) (ABIN1700641)

Target: DGAT2 (Diacylglycerol O-Acyltransferase 2 (DGAT2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DGAT2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-DGAT2 Antikörper (Biotin)

Bindungsspezifität: AA 251-360

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DGAT2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu DGAT2

Target: DGAT2 (Diacylglycerol O-Acyltransferase 2 (DGAT2))

Andere Bezeichnung: DGAT2

Hintergrund:

Synonyms: DGAT2, DGAT2_HUMAN, Diacylglycerol O acyltransferase like protein 2, Diacylglycerol O-acyltransferase 2, Diacylglycerol O-acyltransferase homolog 2 mouse, Diacylglycerol O-acyltransferase homolog 2, Diacylglycerol O-acyltransferase-like protein 2 isoform 1, Diglyceride acyltransferase 2, DKFZp686A15125, GS1999full, HMFN1045.

Background: Glucose and insulin are anabolic signals which upregulate the transcriptions of a series of lipogenic enzymes to convert excess carbohydrate into triglycerides for efficient energy storage. Acyl-coenzyme A:diacylglycerol acyltransferase, also known as DGAT1 and ARGP1, is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT1 plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism, such as intestinal fat absorption, lipoprotein assembly, adipose tissue form-ation and lactation. DGAT2, which has no homology to DGAT1, differs from DGAT1 in that its activity has been shown to be inhibited by MgCl in an in vitro assay. DGAT2 is expressed primarily in liver and white adipose tissue, which suggests that it plays an important role in mammalian triglyceride metabolism.

Gen-ID: 84649

UniProt: Q96PD7