DYX1C1 Antikörper (AA 51-120) (Biotin)

Produktnummer ABIN1700546

Der Kaninchen Polyklonal Anti-DYX1C1-Antikörper wurde für WB, ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet, DYX1C1 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für DYX1C1 Antikörper (AA 51-120) (Biotin) (ABIN1700546)

Target: DYX1C1 (Dyslexia Susceptibility 1 Candidate 1 (DYX1C1))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DYX1C1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-DYX1C1 Antikörper (Biotin)

Bindungsspezifität: AA 51-120

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Chicken,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DYX1C1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu DYX1C1

Target: DYX1C1 (Dyslexia Susceptibility 1 Candidate 1 (DYX1C1))

Andere Bezeichnung: DYX1C1

Hintergrund:

Synonyms: Dyslexia susceptibility 1 candidate 1, Dyslexia susceptibility 1 candidate gene 1 protein, DYX1, DYX1C1, DYXC1, DYXC1_HUMAN, EKN1, FLJ37882, MGC70618, RD.

Background: The gene encoding DYX1C1 maps in the 15q21 region, which is disrupted by a translocation t(2,15)(q11,q21) and segregates with dyslexia. Two sequence changes in DYX1C1, including one involving the translation initiation sequence and an Elk-1 transcription factor binding site (-3G --> A) and a codon (1249G --> T), introduce a premature stop codon and truncate the protein by 4 amino acids. DYX1C1 encodes a nuclear tetratricopeptide repeat domain protein that is dynamically regulated in brain. In human brain, DYX1C1 protein localizes to a fraction of cortical neurons and white matter glial cells. It is also expressed in lung, kidney and testis.

Gen-ID: 161582

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling