MAEA Antikörper (AA 171-250) (Biotin)

Produktnummer ABIN1700521

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MAEA in WB, ELISA, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MAEA Antikörper (AA 171-250) (Biotin) (ABIN1700521)

Target: MAEA (Macrophage erythroblast Attacher (MAEA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAEA Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-MAEA Antikörper (Biotin)

Bindungsspezifität: AA 171-250

Homologie: Human,Mouse,Rat,Dog,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EMP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu MAEA

Target: MAEA (Macrophage erythroblast Attacher (MAEA))

Andere Bezeichnung: MAEA/EMP/HLC10

Hintergrund:

Synonyms: 1110030D19Rik, Cell proliferation inducing gene 5 protein, Cell proliferation-inducing gene 5 protein, EMP, Erythroblast macrophage protein, HLC 10, HLC-10, HLC10, Human lung cancer oncogene 10 protein, Lung cancer related protein 10, lung cancer-related protein 10, Macrophage erythroblast attacher, MAEA, MAEA_HUMAN, MGC93683, PIG5, proliferation-inducing gene 5.

Background: Emp is a 396 amino acid ubiquitously expressed adhesion protein. Expressed as 5 alternatively spliced isoforms, Emp contains one CTLH domain and one LisH domain. Emp can form a complex with F-actin, which is involved regulating actin distribution in erythroblasts and macrophages. Considered to assist with cell division and nuclear architecture, Emp is localized with condensed chromatin at prophase, nuclear spindle poles at metaphase and in the contractile ring during telophase and cytokinesis. Although the exact function of Emp is unknown, Emp is suggested to be involvement in erythroblast-macrophage cell attachment, terminal maturation and enucleation of erythroid cells, and inhibiting apoptosis of erythroblasts.

Gen-ID: 10296