ARL4A Antikörper (AA 21-120) (Biotin)

Produktnummer ABIN1700483

Der Kaninchen Polyklonal Anti-ARL4A-Antikörper wurde für ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet, ARL4A in Proben von Human zu detektieren.

Kurzübersicht für ARL4A Antikörper (AA 21-120) (Biotin) (ABIN1700483)

Target: ARL4A (ADP-Ribosylation Factor-Like 4A (ARL4A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARL4A Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ARL4A Antikörper (Biotin)

Bindungsspezifität: AA 21-120

Homologie: Human,Mouse,Rat,Cow,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ARL4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu ARL4A

Target: ARL4A (ADP-Ribosylation Factor-Like 4A (ARL4A))

Andere Bezeichnung: ARL4

Hintergrund:

Synonyms: ADP ribosylation factor like 4A, ADP-ribosylation factor-like protein 4A, ARL 4, ARL4A, ARL4A_HUMAN.

Background: ADP-ribosylation factors (ARFs) are highly conserved guanine nucleotide-binding proteins that enhance the ADP-ribosyltransferase activity of cholera toxin. ARF_ are important in eukaryotic vesicular trafficking pathways and activating phospholipase D. ARL4 (ADP-ribosylation factor-like protein 4A) is a member of the ARF-like protein (ARL) subfamily of small GTPases. It contains a C terminal nuclear localization signal (NLS) region that interacts with Importin-? ARL4 localizes to the nucleus and is found in a variety of tissues, but is predominantly expressed in spermatogonia and Sertoli cells. It is most closely related to ARL6 and ARL7. Unlike ARFs, ARL4 does not activate the cholera toxin ADP-ribosyltranferase. ARL4 may play a role in neurogenesis during embryonic development and somitogenesis in the early stages of adult spermatogenesis.

Gen-ID: 10124

Pathways: Brown Fat Cell Differentiation