ANTXR1 Antikörper (AA 201-300) (Biotin)

Produktnummer ABIN1700414

Produktdetails anti-ANTXR1 Antikörper (Biotin)

Target: ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

Bindungsspezifität: AA 201-300

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANTXR1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TEM8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu ANTXR1

Target: ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

Andere Bezeichnung: TEM8 (ANTXR1 Produkte)

Synonyme: ANTXR1 antikoerper, ATR antikoerper, TEM8 antikoerper, 2310008J16Rik antikoerper, 2810405N18Rik antikoerper, Antrx1 antikoerper, Tem8 antikoerper, anthrax toxin receptor 1 antikoerper, ANTXR1 antikoerper, Antxr1 antikoerper

Hintergrund:

Synonyms: Anthrax toxin receptor 1, Anthrax toxin receptor 1 precursor, ANTXR 1, ANTXR1, ATR, TEM-8, TEM 8, TEM8, Tumor Endothelial Marker 8, Tumor endothelial marker 8 precursor, ANTR1_HUMAN, Anthrax toxin receptor-1, FLJ11298, FLJ21776.

Background: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]

Gen-ID: 84168

UniProt: Q9H6X2