GMFG Antikörper (AA 51-142) (Biotin)

Produktnummer ABIN1700316

Dieses Anti-GMFG-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GMFG in WB, ELISA, IHC (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für GMFG Antikörper (AA 51-142) (Biotin) (ABIN1700316)

Target: GMFG (Glia Maturation Factor, gamma (GMFG))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GMFG Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-GMFG Antikörper (Biotin)

Bindungsspezifität: AA 51-142

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GMFG/GMF-gamma

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu GMFG

Target: GMFG (Glia Maturation Factor, gamma (GMFG))

Andere Bezeichnung: GMFG/GMF-gamma

Hintergrund:

Synonyms: Glia maturation factor gamma, Glia maturation factor, gamma, GMF GAMMA, GMF-gamma, Gmfg, GMFG_HUMAN, MGC126867.

Background: GMF-gamma is a 142 amino acid protein that belongs to the GMF subfamily of the larger actin-binding protein ADF family. GMF-gamma is expressed predominantly in lung, heart and placenta. GMF-gamma is considered a candidate regulatory growth factor protein, mediating both paracrine and autocrine cell-cell interactions. GMF-gamma is phosphorylated at N-terminal serine, and its phosphorylation is enhanced by coexpression of dominant active Rac 1 and Cdc42. GMF-gamma expression is significantly increased in a cardiac ischemia/reperfusion model where inflammation and angiogenesis take place actively. As a regulator of actin-based cellular functions, GMF-gamma may provide a novel approach to modulate the pathophysiology of cardiovascular diseases. GMF-gamma is primarily found in proliferative and differentiative organs.

Gen-ID: 9535