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CTBS Antikörper (AA 1-100) (Biotin)

CTBS Reaktivität: Maus WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1700252
  • Target Alle CTBS Antikörper anzeigen
    CTBS (Chitobiase, Di-N-Acetyl (CTBS))
    Bindungsspezifität
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reaktivität
    • 17
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 23
    • 3
    • 1
    Kaninchen
    Klonalität
    • 25
    • 2
    Polyklonal
    Konjugat
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CTBS Antikörper ist konjugiert mit Biotin
    Applikation
    • 27
    • 13
    • 13
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CTBS
    Isotyp
    IgG
    Top Product
    Discover our top product CTBS Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    CTBS (Chitobiase, Di-N-Acetyl (CTBS))
    Andere Bezeichnung
    CTBS (CTBS Produkte)
    Synonyme
    CTB antikoerper, 2210401K11Rik antikoerper, chitobiase antikoerper, chitobiase, di-N-acetyl- antikoerper, CTBS antikoerper, Ctbs antikoerper
    Hintergrund

    Synonyms: Chitobiase di N acetyl, CTB, Di N acetylchitobiase, OTTHUMP00000011570, DIAC_HUMAN.

    Background: CTBS is an evolutionarily conserved member of the glycosyl hydrolase 18 family of proteins. Localizing to the lysosome, CTBS plays a role in the degradation of asparagine-linked (Asn-linked) glycoproteins. Glycoproteins are translocated to lysosomes via endocytosis or autophagy where they are broken down by proteases and glycosidases. The catabolism of glycoproteins is an important step in the regular turnover of cellular contents and in maintaining the homeostasis of glycosylation. CTBS functions as a glycosidase that cleaves the reducing end GlcNAc from the core chitobiase unit of oligosaccharides. Before this reaction can occur, AGA (the lysosomal glycosylasparaginase) must first remove the Asn from the Asn-linked glycoprotein to expose the reducing end GlcNAc, thereby allowing CTBS to access the exposed moiety.

    Gen-ID
    1486
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