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GM2A Antikörper (AA 131-193) (Biotin)

This anti-GM2A antibody (ABIN1700012) is a Rabbit Polyclonal antibody detecting GM2A in WB, ELISA, IHC (p), IHC (fro). Suitable for Human, Rat.
Produktnummer ABIN1700012

Quick Overview for GM2A Antikörper (AA 131-193) (Biotin) (ABIN1700012)

Target

Alle GM2A Antikörper anzeigen
GM2A (GM2 Ganglioside Activator (GM2A))

Reaktivität

  • 59
  • 19
  • 19
  • 1
  • 1
Human, Ratte

Wirt

  • 51
  • 8
  • 2
Kaninchen

Klonalität

  • 55
  • 6
Polyklonal

Konjugat

  • 31
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GM2A Antikörper ist konjugiert mit Biotin

Applikation

  • 47
  • 24
  • 14
  • 13
  • 13
  • 7
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 131-193

    Kreuzreaktivität

    Human, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human GM2A/SAP3

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    GM2A (GM2 Ganglioside Activator (GM2A))

    Andere Bezeichnung

    GM2A

    Hintergrund

    Synonyms: SAP-3, GM2-AP, Ganglioside GM2 activator, Cerebroside sulfate activator protein, Sphingolipid activator protein 3, GM2A

    Background: The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 Molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.

    Gen-ID

    2760

    UniProt

    P17900
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