GM2A Antikörper (AA 131-193) (Biotin)

Produktnummer ABIN1700012

This anti-GM2A antibody (ABIN1700012) is a Rabbit Polyclonal antibody detecting GM2A in WB, ELISA, IHC (p), IHC (fro). Suitable for Human, Rat.

Quick Overview for GM2A Antikörper (AA 131-193) (Biotin) (ABIN1700012)

Target: GM2A (GM2 Ganglioside Activator (GM2A))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GM2A Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-GM2A Antikörper (Biotin)

Bindungsspezifität: AA 131-193

Kreuzreaktivität: Human, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GM2A/SAP3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu GM2A

Target: GM2A (GM2 Ganglioside Activator (GM2A))

Andere Bezeichnung: GM2A

Hintergrund:

Synonyms: SAP-3, GM2-AP, Ganglioside GM2 activator, Cerebroside sulfate activator protein, Sphingolipid activator protein 3, GM2A

Background: The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 Molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.

Gen-ID: 2760

UniProt: P17900