Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA) (AA 51-150) Antikörper (Biotin)

Produktnummer ABIN1699992

Dieses Anti--Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von in ELISA, IHC (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA) (AA 51-150) Antikörper (Biotin) (ABIN1699992)

Target: Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails

Bindungsspezifität: AA 51-150

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FARSLA/CML33

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Antigendetails

Target: Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)

Andere Bezeichnung: FARSLA/CML33

Hintergrund:

Synonyms: CML 33, CML33, FARS, FARSA, FARSL, FRSA, PheHA, Phenylalanine tRNA ligase 1 alpha cytoplasmic, Phenylalanine tRNA ligase alpha chain, Phenylalanine tRNA synthetase alpha subunit, Phenylalanine tRNA synthetase like alpha subunit, Phenylalanyl tRNA synthetase alpha chain, Phenylalanyl tRNA synthetase alpha subunit, Phenylalanyl tRNA synthetase like alpha subunit, PheRS.

Background: Aminoacyl-tRNA synthetases consist of a family of enzymes that catalyze the specific aminoacylation of tRNA by their cognate amino acid in the initial step of ribosome-dependent protein biosynthesis. FARSLA, also known as FRSA, CML33, FARSL or PheHA (phenylalanyl-tRNA synthetase, alpha subunit), is a member of the class-II aminoacyl-tRNA synthetase family and is highly expressed in proliferating cells of bone marrow. FARSLA is a cytoplasmic phenylalanine-tRNA synthetase that functions as a heterodimer consisting of a catalytic alpha-subunit and a regulatory beta-subunit. The alpha-subunit is responsible for forming the amino acid binding pocket, mediating the ATP/aminoacyl adenylate binding, and interacts with the acceptor stem of the tRNA. FARSLA functions in a cell cycle-dependent and differentiation-dependent manner.

Gen-ID: 10160