TEX35 Antikörper (AA 101-200) (Biotin)

Produktnummer ABIN1699886

Der Kaninchen Polyklonal Anti-TEX35-Antikörper wurde für WB, ELISA, IHC (fro) und IHC (p) validiert. Er ist geeignet, TEX35 in Proben von Human zu detektieren.

Kurzübersicht für TEX35 Antikörper (AA 101-200) (Biotin) (ABIN1699886)

Target: TEX35 (Testis Expressed 35 (TEX35))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TEX35 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TEX35 Antikörper (Biotin)

Bindungsspezifität: AA 101-200

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf49

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu TEX35

Target: TEX35 (Testis Expressed 35 (TEX35))

Andere Bezeichnung: C1orf49

Hintergrund:

Synonyms: C1orf49, CA049_HUMAN, Chromosome 1 open reading frame 49, RP5-990P15.1, Testis expressed 35, Testis specic conserved gene 24 kDa, TEX35, TSC24, Uncharacterized protein C1orf49.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf49 gene product has been provisionally designated C1orf49 pending further characterization. There are four isoforms of C1orf49 that are produced as a result of alternative splicing events.

Gen-ID: 84066