BPY2 Antikörper (AA 51-106) (Biotin)

Produktnummer ABIN1699873

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BPY2 in WB, ELISA, IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für BPY2 Antikörper (AA 51-106) (Biotin) (ABIN1699873)

Target: BPY2 (Basic Charge, Y-Linked, 2 (BPY2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BPY2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-BPY2 Antikörper (Biotin)

Bindungsspezifität: AA 51-106

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BPY2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu BPY2

Target: BPY2 (Basic Charge, Y-Linked, 2 (BPY2))

Andere Bezeichnung: BPY2

Hintergrund:

Synonyms: Basic charge, Basic charge Y linked 2, Basic charge Y linked 2C, Basic protein on Y chromosome 2, BPY2A, BPY2B, BPY2C, Testis specic basic protein on Y 2, Testis specic basic protein Y 2, Testis-specic basic protein Y 2, Variable charge Y linked 2, Variably charged protein Y 2, VCY2, VCY2_HUMAN, VCY2A, VCY2B, VCY2C, Y-linked 2.

Background: Mammalian spermatogenesis is a complex developmental process. Mutations at multiple loci and in structurally and functionally disparate genes in the genome affect gametogenesis. The analysis of mutations has provided insight into biochemical pathways required for completion of this process. The basic protein on Y chromosome 2 gene (BPY2, also designated VCY2) is located in a frequently deleted azoospermia factor c region. Three copies (paralogs) of the BPY2 gene (BPY2A, BPY2B, BPY2C) reside in the AZFc region. BPY2 protein expression is localized to the nuclei of spermatogonia, spermatocytes and round spermatids, but is absent from elongated spermatids. Impaired expression of BPY2 in infertile men suggests its involvement in male germ cell development. BPY2 interacts with MAP-1S, which shares homology with microtubule-associated proteins (MAPs), suggesting a role for BPY2 within the cytoskeletal network.

Gen-ID: 442867