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HOOK1 Antikörper (AA 551-650) (AbBy Fluor® 647)

This anti-HOOK1 antibody (ABIN1698883) is a Rabbit Polyclonal antibody detecting HOOK1 in WB, IF (cc), IF (p). Suitable for Mouse.
Produktnummer ABIN1698883

Quick Overview for HOOK1 Antikörper (AA 551-650) (AbBy Fluor® 647) (ABIN1698883)

Target

Alle HOOK1 Antikörper anzeigen
HOOK1 (Hook Homolog 1 (HOOK1))

Reaktivität

  • 29
  • 21
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Maus

Wirt

  • 39
  • 4
Kaninchen

Klonalität

  • 41
  • 2
Polyklonal

Konjugat

  • 21
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HOOK1 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation

  • 38
  • 20
  • 12
  • 12
  • 6
  • 5
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 551-650

    Kreuzreaktivität

    Maus

    Homologie

    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human HOOK1

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    HOOK1 (Hook Homolog 1 (HOOK1))

    Andere Bezeichnung

    HOOK1

    Hintergrund

    Synonyms: A930033L17Rik, Abnormal spermatozoon head shape, azh, h-hook1, hHK1, HK1, HOOK 1, Hook homolog 1 Drosophila, Hook1, HOOK1_HUMAN, MGC10642, OTTHUMP00000010548, OTTMUSP00000008480, Protein Hook homolog 1, RP23-80B16.4.

    Background: Microtubules mediate the spatial organization of diverse membrane-trafficking systems. The HOOK proteins, HOOK1, HOOK2 and HOOK3, comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. HOOK1, a cytoskeletal linker protein, may play a role in endocytic membrane trafficking. It exists as a homodimer, most likely mediated through its central coiled-coil domain. HOOK1 interacts with VPS18 and is required for spermatid differentiation, in which it is most likely involved in the positioning of the manchette microtubules and the flagellum. HOOK1 localizes primarily to the cytoplasm and does not associate with the Golgi complex, unlike HOOK3, which participates in the organization of the cis-Golgi compartment.

    Gen-ID

    51361

    Pathways

    SARS-CoV-2 Protein Interaktom
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