DUSP10 Antikörper (AA 161-260) (AbBy Fluor® 647)

Produktnummer ABIN1698832

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DUSP10 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für DUSP10 Antikörper (AA 161-260) (AbBy Fluor® 647) (ABIN1698832)

Target: DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP10 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-DUSP10 Antikörper (AbBy Fluor® 647)

Bindungsspezifität: AA 161-260

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DUSP10/MKP5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DUSP10

Target: DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))

Andere Bezeichnung: DUSP10/MKP5

Hintergrund:

Synonyms: Dual specicity phosphatase 10, Dual specicity phosphatase MKP 5, Dual specicity phosphatase MKP5, Dual specicity protein phosphatase 10, DUS10_HUMAN, DUSP 10, DUSP10, DUSP10 protein, MAP kinase phosphatase 5, Mitogen activated protein kinase phosphatase 5, Mitogen-activated protein kinase phosphatase 5, MKP 5, MKP-5, MKP5, Serine/threonine specic protein phosphatase.

Background: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. MKP-5 preferentially binds to p38, but also to SAPK/JNK. It is ubiquitously expressed and localizes to both the cytoplasm and the nucleus. MKP-5 has been implicated in cell proliferation and apoptosis, tumor invasion and immune responses.

Gen-ID: 11221