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LIMD1 Antikörper (AA 21-120) (AbBy Fluor® 555)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch LIMD1 in IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Maus.
Produktnummer ABIN1697191

Kurzübersicht für LIMD1 Antikörper (AA 21-120) (AbBy Fluor® 555) (ABIN1697191)

Target

Alle LIMD1 Antikörper anzeigen
LIMD1 (LIM Domains Containing 1 (LIMD1))

Reaktivität

  • 28
  • 21
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Maus

Wirt

  • 35
  • 2
Kaninchen

Klonalität

  • 35
  • 2
Polyklonal

Konjugat

  • 19
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser LIMD1 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation

  • 20
  • 14
  • 12
  • 12
  • 12
  • 8
  • 4
  • 3
  • 2
  • 2
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120

    Kreuzreaktivität

    Maus

    Homologie

    Human,Rat,Cow,Sheep,Pig,Chicken,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Limd1

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    LIMD1 (LIM Domains Containing 1 (LIMD1))

    Andere Bezeichnung

    Limd1

    Hintergrund

    Synonyms: AW822033, D9Ertd192e, LIM domain-containing protein 1, LIM domains containing 1, LIMD1, LIMD1_HUMAN, OTTHUMP00000164657, OTTHUMP00000210317, rCG_25194.

    Background: The Zyxin family of proteins contains five members: Ajuba, Limd1, LPP, TRIP6 and Zyxin. Limd1 (LIM domain-containing protein 1) is a ubiquitously expressed tumor suppressor containing 3 LIM zinc-binding domains. LIM domains consist of a cysteine-rich consensus sequence containing two distinct zinc-binding subdomains, which mediate protein-protein interactions. Limd1 interacts with the proteins SQSTM1, Rb, p62 and TRAF6. Limd1 was first identified when the deletion of its gene was noted in some cervical cancers. Limd1 blocks in vitro and in vivo tumor growth and is down-regulated in lung cancer. Limd1 may regulate osteoclast development under stressful conditions via its interactions with TRAF6 and p62.

    Gen-ID

    8994

    Pathways

    Ribonucleoprotein Complex Subunit Organization
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