ITPA Antikörper (AA 1-100) (AbBy Fluor® 555)

Produktnummer ABIN1696723

This anti-ITPA antibody (ABIN1696723) is a Rabbit Polyclonal antibody detecting ITPA in WB, IF (cc), IF (p). Suitable for Human.

Quick Overview for ITPA Antikörper (AA 1-100) (AbBy Fluor® 555) (ABIN1696723)

Target: ITPA (Inosine Triphosphatase (ITPA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITPA Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ITPA Antikörper (AbBy Fluor® 555)

Bindungsspezifität: AA 1-100

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Inosine triphosphate pyrophosphatase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ITPA

Target: ITPA (Inosine Triphosphatase (ITPA))

Andere Bezeichnung: Inosine triphosphate pyrophosphatase

Hintergrund:

Synonyms: ITPase, C20orf37, dJ794I6.3, HLC14-06-P, Inosine triphosphatase nucleoside triphosphate pyrophosphatase, Inosine triphosphatase, inosine triphosphatase-A, Inosine triphosphate pyrophosphatase, Inosine triphosphate pyrophosphohydrolase, Itpa, ITPA_HUMAN, ITPase, My049, My049 protein, Non canonical purine NTP pyrophosphatase, Non standard purine NTP pyrophosphatase, NTPase, nucleoside triphosphate diphosphatase, Nucleoside triphosphate pyrophosphatase, OK/SW-cl.9, OTTHUMP00000030094, OTTHUMP00000160459, Putative oncogene protein hlc14-06-p.

Background: ITPase (inosine triphosphate pyrophosphatase) is also known as putative oncogene protein hlc14-06-p or ITPA (inosine triphosphatase (nucleoside triphosphate pyrophosphatase)) and is a 194 amino acid protein. ITPase is abundantly expressed in heart, liver, sex glands, thyroid and adrenal gland, and is localized to the cytoplasm in the cell. ITPase catalyzes the pyrophosphohydrolysis of both ITP (inosine triphosphate) and dITP (deoxyinosine triphosphate) to IMP (inosine monophosphate) and diphosphate. IMP can be used as a substrate for purine nucleotide pathways. IMP can be phosphorylated to ITP, and ITPase can regulate the concentration of ITP in the cell by converting ITP back to IMP. Defects in ITPase result in ITPase deficiency which is thought to be inherited and is characterized by an over-accumulation of ITP in erythocytes, leukocytes and fibroblasts.

Gen-ID: 3704