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DOK7 Antikörper (AA 21-120) (AbBy Fluor® 555)

This anti-DOK7 antibody (ABIN1696534) is a Rabbit Polyclonal antibody detecting DOK7 in WB, IF (cc), IF (p). Suitable for Rat.
Produktnummer ABIN1696534

Quick Overview for DOK7 Antikörper (AA 21-120) (AbBy Fluor® 555) (ABIN1696534)

Target

Alle DOK7 Antikörper anzeigen
DOK7 (Docking Protein 7 (DOK7))

Reaktivität

  • 32
  • 22
  • 17
Ratte

Wirt

  • 46
  • 4
  • 1
  • 1
Kaninchen

Klonalität

  • 48
  • 4
Polyklonal

Konjugat

  • 22
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DOK7 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation

  • 41
  • 20
  • 12
  • 12
  • 10
  • 8
  • 7
  • 5
  • 3
  • 3
  • 3
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 21-120

    Kreuzreaktivität

    Ratte

    Homologie

    Human,Mouse,Dog,Cow,Sheep,Pig,Horse

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human DOK7

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    DOK7 (Docking Protein 7 (DOK7))

    Andere Bezeichnung

    DOK7

    Hintergrund

    Synonyms: Docking protein 7, DOK 7, DOK7, DOK7_HUMAN, Downstream of tyrosine kinase 7, Protein Dok-7.

    Background: The downstream of kinase family (Dok1-7) are members of a class of docking? proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Based on their similarities, the Dok family of proteins can be divided into three subgroups: Dok-1/2/3, Dok-4/5/6 and Dok-7. Through its interaction with muscle-specific receptor kinase (MuSK), Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation. Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters. Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA) recessively inherited disorders characterized by muscle weakness.

    Pathways

    Skeletal Muscle Fiber Development
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