PHC1 Antikörper (AA 751-900) (AbBy Fluor® 488)

Produktnummer ABIN1695789

This anti-PHC1 antibody (ABIN1695789) is a Rabbit Polyclonal antibody detecting PHC1 in IF (cc), IF (p). Suitable for Human.

Kurzübersicht für PHC1 Antikörper (AA 751-900) (AbBy Fluor® 488) (ABIN1695789)

Target: PHC1 (Polyhomeotic-Like 1 (PHC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHC1 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-PHC1 Antikörper (AbBy Fluor® 488)

Bindungsspezifität: AA 751-900

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EDR1/PHC1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PHC1

Target: PHC1 (Polyhomeotic-Like 1 (PHC1))

Andere Bezeichnung: EDR1/PHC1

Hintergrund:

Synonyms: Early development regulatory protein 1, EDR1 PH1, hPH1, mPH1, PH1, Polyhomeotic-like protein 1, Rae28, PHC1_HUMAN.

Background: PHC1 is a 1,004 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Existing as a homodimer, PHC1 contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain. PHC1 is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome.

Gen-ID: 1911