EXOSC7 Antikörper (AA 21-120) (AbBy Fluor® 488)

Produktnummer ABIN1695202

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch EXOSC7 in IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für EXOSC7 Antikörper (AA 21-120) (AbBy Fluor® 488) (ABIN1695202)

Target: EXOSC7 (Exosome Component 7 (EXOSC7))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EXOSC7 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-EXOSC7 Antikörper (AbBy Fluor® 488)

Bindungsspezifität: AA 21-120

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EXOSC7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu EXOSC7

Target: EXOSC7 (Exosome Component 7 (EXOSC7))

Andere Bezeichnung: EXOSC7

Hintergrund:

Synonyms: EAP1, EXOS7_HUMAN, Exosc7, Exosome complex component RRP42, Exosome complex exonuclease RRP42, Exosome component 7, FLJ26543, hRrp42p, KIAA0116, p8, Ribosomal RNA processing protein 42, Ribosomal RNA-processing protein 42, RRP42, Rrp42p.

Background: The exosome is a multisubunit complex of 3? to 5? exoribonucleases. It is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements in their untranslated 3? region. EXOSC7 (exosome component 7), also known as p8, EAP1, RRP42 (Ribosomal RNA-processing protein 42), Rrp42p or hRrp42p, is a component of the exosome multienzyme ribonuclease complex. It belongs to the RNase PH family and localizes to the nucleolus. EXOSC7 is one of the six RNase-PH domain subunits of the exosome. Together, these six subunits form a PNPase-like ring. EXOSC7 is required for the processing of the 7S pre-RNA.

Gen-ID: 23016