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GEMIN4 Antikörper (AA 251-350) (Alexa Fluor 350)

GEMIN4 Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN1693685
$438.15
Zzgl. Versandkosten $45.00
100 μL
Lieferung in 11 bis 16 Werktagen
  • Target Alle GEMIN4 Antikörper anzeigen
    GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))
    Bindungsspezifität
    • 16
    • 14
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 251-350
    Reaktivität
    • 49
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 45
    • 4
    Kaninchen
    Klonalität
    • 46
    • 3
    Polyklonal
    Konjugat
    • 18
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GEMIN4 Antikörper ist konjugiert mit Alexa Fluor 350
    Applikation
    • 30
    • 26
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Mouse,Rat,Dog,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Gemin 4
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Haltbarkeit
    12 months
  • Target
    GEMIN4 (Gem (Nuclear Organelle) Associated Protein 4 (GEMIN4))
    Andere Bezeichnung
    Gemin 4 (GEMIN4 Produkte)
    Synonyme
    HC56, HCAP1, HHRF-1, p97, 4932415L08Rik, AU015359, im:7143815, wu:fc41c09, zgc:110169, GEMIN4, RGD1563715, gem nuclear organelle associated protein 4, gem (nuclear organelle) associated protein 4, GEMIN4, Gemin4, gemin4
    Hintergrund

    Gemin4 is a component of the SMN core complex which, while in the cytoplasm, plays an essential role in ribonucleoprotein (snRNP) assembly, including the biogenesis, delivery and recycling of snRNPs to the spliceosome. In the nucleus, where SMN is required for pre-mRNA splicing, Gemin4 concentrates next to coiled bodies in subnuclear structures called gems, that are highly enriched in splicosomal snRNPs, and in the nucleolus. Deletion or loss-of-function mutations in the SMN lead to the neurodegenerative disease spinal muscular atrophy (SMA). The human Gemin4 maps to chromosome 17p13.

    Subcellular location: Cytoplasm

    Synonyms: Gemin4, Gemin-4, Component of gems 4, Gem associated protein 4, HC56, HHRF 1, GEMI4_HUMAN.

    Gen-ID
    50628
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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