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KNDC1 Antikörper (AA 1601-1749) (Alexa Fluor 350)

KNDC1 Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN1693515
$438.15
Zzgl. Versandkosten $45.00
100 μL
Lieferung in 11 bis 16 Werktagen
  • Target Alle KNDC1 Antikörper anzeigen
    KNDC1 (Kinase Non-Catalytic C-Lobe Domain (KIND) Containing 1 (KNDC1))
    Bindungsspezifität
    • 14
    • 1
    • 1
    AA 1601-1749
    Reaktivität
    Human
    Wirt
    • 16
    Kaninchen
    Klonalität
    • 16
    Polyklonal
    Konjugat
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KNDC1 Antikörper ist konjugiert mit Alexa Fluor 350
    Applikation
    • 12
    • 12
    • 5
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Pig,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human KNDC1
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Haltbarkeit
    12 months
  • Target
    KNDC1 (Kinase Non-Catalytic C-Lobe Domain (KIND) Containing 1 (KNDC1))
    Andere Bezeichnung
    KNDC1 (KNDC1 Produkte)
    Synonyme
    C10orf23, RASGEF2, bB439H18.3, 2410012C07Rik, B830014K08Rik, VKIND, very-kind, RGD1565261, kinase non-catalytic C-lobe domain containing 1, kinase non-catalytic C-lobe domain (KIND) containing 1, protein very KIND, KNDC1, Kndc1, LOC536342
    Hintergrund

    KNDC1 is a 1,749 amino acid protein that contains two KIND domains and an N-terminal Ras-GEF domain. Expressed in the cerebral cortex, KNDC1 is a likely guanine nucleotide exchange factor (GEF). Existing as six alternatively spliced isoforms, the gene encoding KNDC1 maps to human chromosome 10q26.3 and mouse chromosome 7 F4. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5 % of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman?s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

    Subcellular location: Cytoplasm, Nucleus

    Synonyms: Cerebral protein 9, FLJ25027, hucep-9, KIAA1768, Kinase non-catalytic C-lobe domain-containing protein 1, KIND domain-containing protein 1, KNDC1, Protein very KIND, Ras-GEF domain-containing family member 2, RASGEF2, VKIND, VKIND_HUMAN, bB439H18.3, C10orf23.

    Gen-ID
    85442
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