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Supervillin Antikörper (AA 51-150) (Alexa Fluor 350)

SVIL Reaktivität: Maus IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN1693466
$438.15
Zzgl. Versandkosten $45.00
100 μL
Lieferung in 11 bis 16 Werktagen
  • Target Alle Supervillin (SVIL) Antikörper anzeigen
    Supervillin (SVIL)
    Bindungsspezifität
    • 14
    • 5
    • 3
    • 2
    • 1
    • 1
    AA 51-150
    Reaktivität
    • 16
    • 15
    Maus
    Wirt
    • 24
    • 5
    • 1
    Kaninchen
    Klonalität
    • 26
    • 4
    Polyklonal
    Konjugat
    • 10
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Supervillin Antikörper ist konjugiert mit Alexa Fluor 350
    Applikation
    • 19
    • 12
    • 12
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Supervillin
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Haltbarkeit
    12 months
  • Target
    Supervillin (SVIL)
    Andere Bezeichnung
    Supervillin (SVIL Produkte)
    Synonyme
    sb:cb867, svil, wu:fd05a09, SVIL, DKFZp468F0819, AU024053, B430302E16Rik, supervillin a, supervillin, supervillin, putative, svila, SVIL, LOC5577073, CpipJ_CPIJ003700, Smp_148580, svil, Svil
    Hintergrund

    Forms a high-affinity link between the actin cytoskeleton and the membrane. Isoform 1 (archvillin) is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function. Isoform 2 may be involved in modulation of focal adhesions. Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6. Plays a role in cytokinesis through KIF14 interaction (By similarity).

    Subcellular location: Cytoplasm, Cell membrane

    Synonyms: Supervillin, Archvillin, p205/p250, SVIL

    Gen-ID
    6840
    UniProt
    O95425
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