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PTCHD2 Antikörper (AA 401-500) (Alexa Fluor 350)

PTCHD2 Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN1693454
$438.15
Zzgl. Versandkosten $45.00
100 μL
Lieferung in 11 bis 16 Werktagen
  • Target Alle PTCHD2 Antikörper anzeigen
    PTCHD2 (Patched Domain Containing 2 (PTCHD2))
    Bindungsspezifität
    • 14
    • 11
    • 8
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 401-500
    Reaktivität
    • 42
    • 6
    • 5
    Human
    Wirt
    • 42
    Kaninchen
    Klonalität
    • 42
    Polyklonal
    Konjugat
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PTCHD2 Antikörper ist konjugiert mit Alexa Fluor 350
    Applikation
    • 27
    • 22
    • 12
    • 12
    • 9
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PTCHD2/DISP3
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Haltbarkeit
    12 months
  • Target
    PTCHD2 (Patched Domain Containing 2 (PTCHD2))
    Andere Bezeichnung
    PTCHD2/DISP3 (PTCHD2 Produkte)
    Synonyme
    DISP3, G630052C06Rik, RNDEu-2, RGD1305820, dispatched RND transporter family member 3, patched domain-containing protein 2, si:dkey-32e23.6, DISP3, LOC100082708, si:dkey-32e23.6, disp3, Disp3
    Hintergrund

    PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.

    Subcellular location: Cell membrane

    Synonyms: DISP3, Dispatched, drosophila, homolog of, 3, G630052C06Rik, hCG_24779, KIAA1337, Patched domain-containing protein 2, Protein dispatched homolog 3, Ptchd2, PTHD2_HUMAN, RGD1305820, RND-type protein RNDEu-2, RNDEu-2, patched domain containing 2, RP23-157B15.1.

    Gen-ID
    57540
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