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CHTOP Antikörper (AA 31-130) (Alexa Fluor 350)

CHTOP Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN1693355
$438.15
Zzgl. Versandkosten $45.00
100 μL
Lieferung in 11 bis 16 Werktagen
  • Target Alle CHTOP Antikörper anzeigen
    CHTOP (Chromatin Target of PRMT1 (CHTOP))
    Bindungsspezifität
    • 14
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 31-130
    Reaktivität
    • 30
    • 13
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 27
    • 6
    • 2
    Kaninchen
    Klonalität
    • 27
    • 8
    Polyklonal
    Konjugat
    • 18
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CHTOP Antikörper ist konjugiert mit Alexa Fluor 350
    Applikation
    • 17
    • 12
    • 12
    • 9
    • 9
    • 7
    • 4
    • 4
    • 4
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human C1orf77
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Haltbarkeit
    12 months
  • Target
    CHTOP (Chromatin Target of PRMT1 (CHTOP))
    Andere Bezeichnung
    C1orf77 (CHTOP Produkte)
    Synonyme
    C1orf77, FL-SRAG, FOP, RP1-178F15.2, SRAG, SRAG-3, SRAG-5, pp7704, 2500003M10Rik, C81330, Fop, Srag, C25H1orf77, C3H1orf77, c1orf77, chtop, fop, srag, zgc:153909, chromatin target of PRMT1, chromatin target of PRMT1 S homeolog, chromatin target of PRMT1 protein, chromatin target of PRMT1b, CHTOP, Chtop, chtop.S, LOC100344922, chtopb
    Hintergrund

    C1orf77, also known as Friend of PRMT1 protein, is a 248 amino acid protein that plays an essential role in the ligand-dependent activation of estrogen receptor target genes. C1orf77 is tightly associated with chromatin and is modified by both asymmetric and symmetric arginine methylation. Depletion of C1orf77 results in almost complete block of estradiol-induced promter occupancy by the estrogen receptor. Also, complete knockdown of C1orf77 mRNA in adult erythroid progenitors stongly induces fetal hemoglobin, suggesting that C1orf77 is a critical modulator of _-globin gene expression. There are two isoforms of C1orf77 that are produced as a result of alternative splicing events. The gene encoding C1orf77 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.

    Subcellular location: Nucleus

    Synonyms: Chromatin target of PRMT1 protein, Chromosome 1 open reading frame 77, CHTOP, CHTOP_HUMAN, DKFZp547E1010, FOP, Friend of PRMT1 protein, MGC131924, MGC86949, OTTHUMP00000035122, OTTHUMP00000035123, Pp7704, RP1 178F15.2, Small arginine- and glycine-rich protein, Small protein rich in arginine and glycine, SRAG.

    Gen-ID
    26097
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