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GAPVD1 Antikörper (AA 1151-1250) (Alexa Fluor 350)

GAPVD1 Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN1693229
$438.15
Zzgl. Versandkosten $45.00
100 μL
Lieferung in 11 bis 16 Werktagen
  • Target Alle GAPVD1 Antikörper anzeigen
    GAPVD1 (GTPase Activating Protein and VPS9 Domains 1 (GAPVD1))
    Bindungsspezifität
    • 14
    • 2
    • 2
    • 1
    • 1
    AA 1151-1250
    Reaktivität
    • 22
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 21
    • 2
    Kaninchen
    Klonalität
    • 23
    Polyklonal
    Konjugat
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GAPVD1 Antikörper ist konjugiert mit Alexa Fluor 350
    Applikation
    • 12
    • 12
    • 10
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GAPVD1
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Haltbarkeit
    12 months
  • Target
    GAPVD1 (GTPase Activating Protein and VPS9 Domains 1 (GAPVD1))
    Andere Bezeichnung
    GAPVD1 (GAPVD1 Produkte)
    Synonyme
    zgc:92666, GAPEX5, RAP6, 2010005B09Rik, 4432404J10Rik, AW108497, Gapex-5, RME-6, mKIAA1521, RGD1307479, GTPase activating protein and VPS9 domains 1, GTPase activating protein and VPS9 domains 1 S homeolog, LOAG_00609, GAPVD1, gapvd1, gapvd1.S, Gapvd1
    Hintergrund

    GAPVD1 is a 1478 amino acid peripheral membrane protein that acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF). GAPVD1 participates in many processes such as insulin receptor internalization, Glut4 trafficking and endocytosis. In addition, depletion of GAPVD1 leads to delayed EGFR degradation by mediating receptor ubiquination through its RGD domain, suggesting that it may be an important mediator of carcinogenesis resulting from Ras protein mutations. There are six isoforms of GAPVD1 that are produced as a result of alternative splicing events.

    Subcellular location: Cytoplasm, Cell membrane

    Synonyms: GAPEX 5, GAPVD1, GTPase activating protein and VPS9 domains 1, KIAA1521, Rab5 activating protein 6, RAP6, GAPD1_HUMAN.

    Gen-ID
    26130
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