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TMEM245 Antikörper (AA 201-300) (Alexa Fluor 350)

TMEM245 Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN1692876
$438.15
Zzgl. Versandkosten $45.00
100 μL
Lieferung in 11 bis 16 Werktagen
  • Target See all TMEM245 products
    TMEM245 (Transmembrane Protein 245 (TMEM245))
    Bindungsspezifität
    AA 201-300
    Reaktivität
    Human
    Wirt
    • 14
    Kaninchen
    Klonalität
    • 14
    Polyklonal
    Konjugat
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TMEM245 Antikörper ist konjugiert mit Alexa Fluor 350
    Applikation
    • 12
    • 12
    • 3
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Dog,Cow,Sheep
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human C9orf5
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Haltbarkeit
    12 months
  • Target
    TMEM245 (Transmembrane Protein 245 (TMEM245))
    Andere Bezeichnung
    C9orf5 (TMEM245 Produkte)
    Synonyme
    C9orf5, CG-2, CG2, transmembrane protein 245, TMEM245
    Hintergrund

    C9orf5 (chromosome 9 open reading frame 5), also known as CG2, is a 911 amino acid multi-pass membrane protein that is widely expressed and exists as four alternatively spliced isoforms. The gene encoding C9orf5 maps to human chromosome 9, which consists of about 145 million bases, represents 4 % of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

    Subcellular location: Cell membrane

    Synonyms: C9orf5, TM245_HUMAN, Protein CG-2, Transmembrane protein C9orf5,

    Gen-ID
    23731
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