Lethal (2) I16 (L(2)I16) (AA 701-785) Antikörper (AbBy Fluor® 350)

Produktnummer ABIN1692773

Der Kaninchen Polyklonal anti-Lethal (2) I16 Antikörper wird verwendet zum Nachweis von Lethal (2) I16 in Proben von Maus. Er wurde validiert für WB, IF (cc) und IF (p).

Kurzübersicht für Lethal (2) I16 (L(2)I16) (AA 701-785) Antikörper (AbBy Fluor® 350) (ABIN1692773)

Target: Lethal (2) I16 (L(2)I16)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: AbBy Fluor® 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails

Bindungsspezifität: AA 701-785

Kreuzreaktivität: Maus

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IFI16

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Lethal (2) I16 (L(2)I16)

Andere Bezeichnung: I16

Hintergrund:

Synonyms: I16, Gamma interferon inducible protein 16, Gamma-interferon-inducible protein i16, IF16_HUMAN, i204, NGIP1, interferon activated gene 204, Interferon gamma induced protein I 16, Interferon gamma inducible protein 16, Interferon-inducible myeloid dferentiation transcriptional activator, p204, PYHIN2.

Background: IFI16 is a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gen-ID: 3428

UniProt: Q16666