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BCAN Antikörper (AA 219-655)

BCAN Reaktivität: Ratte ICC, IF, WB Wirt: Maus Monoclonal S294A-6 unconjugated
Produktnummer ABIN1686637
$474.50
Zzgl. Versandkosten $45.00
100 μg
Lieferung in 3 bis 4 Werktagen
  • Target Alle BCAN Antikörper anzeigen
    BCAN (Brevican (BCAN))
    Bindungsspezifität
    • 12
    • 9
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 219-655
    Reaktivität
    • 36
    • 17
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 30
    • 20
    • 2
    Maus
    Klonalität
    • 34
    • 18
    Monoklonal
    Konjugat
    • 22
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BCAN Antikörper ist unkonjugiert
    Applikation
    • 41
    • 24
    • 21
    • 15
    • 14
    • 11
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
    Spezifität
    Detects ~140 kDa (and smaller due to proteolytic cleavage).
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Protein G Purified
    Immunogen
    Fusion protein amino acids 219-655 of rat Brevican
    Klon
    S294A-6
    Isotyp
    IgG2b
  • Applikationshinweise
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    1 μg/ml of ABIN1686637 was sufficient for detection of Brevican in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C
  • Target
    BCAN (Brevican (BCAN))
    Andere Bezeichnung
    Brevican (BCAN Produkte)
    Synonyme
    fi32a12, wu:fi32a12, BCAN, Xbcan, Cspg7, ALPBRE, BEHAB, CSPG7, brevican, brevican L homeolog, bcan, BCAN, bcan.L, Bcan
    Hintergrund
    Brevican is the most abundant chondroitin sulfate proteoglycan in the extracellular matrix of the adult brain. It is a member of the lectican family of aggregating extracellular matrix proteoglycans that bear chondroitin sulfate (CS) chains. It is highly expressed in the central nervous system and is thought to stabilize synapses and inhibit neural plasticity. Brevican is secreted from astrocytes and neurons as a 145 kD core protein that bears up to three, covalently-linked, CS chains. It is also is secreted as a 145 kD core protein without CS chains. When cleaved by extracellular glutamyl endopeptidases, the ADAMTSs, a 55 kD N-terminal fragment is formed that contains the unique C terminal epitope EAMESE.
    Gen-ID
    25393
    NCBI Accession
    NP_001028837
    UniProt
    P55068
    Pathways
    Glycosaminoglycan Metabolic Process
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